Stem Cell Types

The Center for Stem Cell and Regenerative Medicine brings together established investigators from five institutions with proven expertise in stem cell research and clinical studies. Due to the impressive breadth of investigator expertise, the scope of non-embryonic stem cell types under study within the Center is comprised of ten cell types:

ASC	Adipose Stem Cells
CSC	Cochlear Stem Cells
CTP	Connective Tissue Progenitor Cells
HSC	Hematopoietic Stem Cells
HB1	Hemangioblast (AC133) derived from umbilical cord blood
MAPC	Multi-potent Adult Stem Cells
MSC	Mesenchymal Stem Cells
NSC	Neural Stem Sells/oligodendrocyte progenitors
SKMB	Skeletal Myoblasts
UCB	Umbilical Cord Blood Derived Stem Cells

This collection of stem cells is being investigated for therapeutic uses in musculoskeletal, cardiovascular, hematopoietic and neurological disorders.

Orthopedic and Musculoskeletal	CTP, MAPC, MSC, SKMB	Bone and cartilage repair, MSC homing factors, myoblast homing using surface molecule "painting" -- for fractures, joint disease, muscular dystrophy.
Cardiovascular and vascular	HB1, HSC, MAPC, SKMB, UCB	Myocardial regeneration with cell homing, differentiation and regeneration, vascular remodeling -- for ischemic, congestive and dilated cardiomyopathy.
Hematopoietic and cancer	HB1, HSC, MSC, UCB	UCB (umbilical cord blood) stem cell expansion and transplantation, cytokine directed differentiation for GVL (graft vs. leukemia), marrow reconstitution and stem cell selection, HSC gene transfer, MSC modulation of GVHD (graft vs. host disease), -- for curing cancer allogeneic transplantation, correction of genetic diseases and protection from chemotherapy.
Neurodegenerative and neurological	MAPC, NSC	Cell implantation into brain and spinal cord for neuronal or glial replacement therapy in Neurodegenerative disorders - Huntington's disease, multiple sclerosis, amyotropic lateral sclerosis and spinal cord injury.