Photo of Kenneth Cooke M.D.Kenneth R. Cooke, M.D.

Associate Professor in Pediatrics
Ohio Eminent Scholar in Stem Cell and
Regenerative Medicine
Rainbow and Hillary Vassil Endowed Professor in Stem Cell Research and Pediatric Oncology
Director, Pediatric Bone Marrow Transplant Program
Wolstein Research Building
2103 Cornell Rd
Cleveland, OH 44106
Phone: (216) 368-1481
e-mail: kenneth.cooke@uhhospitals.org

KC and the Sunshine Band: Laboratory
Rainbow’s Blood and Marrow Transplantation Program


Education:

1982 - 1986 - BA, University of Pennsylvania, College                        of Arts and Sciences, Philadelphia, PA
1986 - 1990 - MD, UMDNJ Robert Wood Johnson Medical School, Piscataway, NJ

Post-Doctoral Training:

Internship and Residency:

1990 - 1991 - Intern in Pediatrics, The Children's Hospital of Philadelphia, PA
1991 - 1993 - Resident in Pediatrics, The Children's Hospital of Philadelphia, PA

Clinical and Research Fellowships:

1993 - 1994 - Clinical Fellow in Pediatric Hematology and Oncology, The Dana-Farber                        Cancer Institute, and Children's Hospital, Boston, MA
1994 - 1996 - Post-Doctoral Fellow in Pediatric Hematology and Oncology, The Dana-
                       Farber Cancer Institute, and Children's Hospital, Boston, MA

Academic Appointments:

1996 - 1999 - Instructor of Pediatrics, Harvard Medical School, Dana-Farber Cancer                        Institute and Children's Hospital, Boston, MA
1999 - 2007 - Assistant Professor, Department of Pediatrics and Communicable                        Diseases, Division of Hematology / Oncology, C.S. Mott Children's                        Hospital, University of Michigan Medical Center, Ann Arbor, MI
2005 - 2007 - Associate Professor, Department of Pediatrics and Communicable                        Diseases, Division of Hematology / Oncology, C.S. Mott Children's                        Hospital, University of Michigan Medical Center, Ann Arbor, MI
2007-              Associate Professor, Department of Pediatrics, Case Western Reserve                        School of Medicine, Rainbow Babies and Children’s Hospital, Cleveland,                        OH
2007-              Director, Pediatric Blood and Marrow Transplantation Program, Rainbow                        Babies and Children’s Hospital, Cleveland, OH
2007-              Director, Multi-disciplinary Program in Graft-versus-Host Disease, Ireland                        Cancer Center, Cleveland, OH
2007-              Medical Director, Stem Cell Core Facility, Case Comprehensive Cancer                        Center Cleveland, OH

Clinical/Hospital Appointments:

2007-              Rainbow Babies and Children’s Hospital, University Hospitals Case                        Medical Center, Cleveland, OH (pending)

Memberships in Professional Societies:

1999-               American Society of Hematology
2000-               American Medical Association
2000-               The American Association of Immunologists
2001-               The Society for Pediatric Research       
2002-               The American Society for Blood and Marrow Transplantation
2002-               The American Society of Pediatric Hematology/Oncology
2007-               Case Comprehensive Cancer Center
2008-               American Society of Clinical Investigation

Major Research Interests:

1. Idiopathic pneumonia syndrome
2. Graft-versus-host disease
3. Bone marrow transplantation
4. Inflammatory cytokines/chemokines

Clinical Trials:

1. Etanercept for the Treatment of Subacute Pulmonary Dysfunction Following Allogeneic Stem Cell Transplantation, A Phase II Study. (IRB approved, open) PI: Yanik, G, and Cooke, KR.

2. Addition of Etanercept to Standard GVHD Prophylaxis in Patients Undergoing a Full Intensity, Unrelated Donor Hematopoietic Stem Cell Transplant for the Prevention of Transplant Related Complications. (IRB approved, open) Co-Investigator: Cooke, KR.

3. A Randomized Double-Blind, Placebo-Controlled Trial of Soluble Tumor Necrosis Factor Receptor: Enbrel (Etanercept) for the Treatment of Acute Non-Infectious Pulmonary Dysfunction (Idiopathic Pneumonia Syndrome) Following Allogeneic Cell Transplantation: BMT CTN PROTOCOL 0403. PI: Yanik, G, and Cooke, KR.

4. Soluble Tumor Necrosis Factor Receptor: Enbrel® (Etanercept) for the Treatment of AcuteNon-Infectious Pulmonary Dysfunction (Idiopathic Pneumonia Syndrome) FollowingAllogeneic Stem Cell Transplantation. A phase II study: Children’s Oncology Group # ASCT0521. PI Yanik, G. and Cooke, KR.

Honors and Awards:

1996                Mentored Clinical Scientist Development Award, NHLBI
1999                The National Marrow Donor Program, Amy Strelzer Manasevit Scholars                         Award for the Study of Post-Transplant Complications
1999                Fellow of the Robert Wood Johnson Minority Medical Faculty                         Development Program
2001                The Leukemia and Lymphoma Society Translational Research Award
2004                University of Michigan, Undergraduate Research Opportunity Program,                         Faculty Recognition Award for Outstanding Research Mentorship
2004                University of Michigan, C.S. Mott Children’s Hospital Service Award for                         Excellence in Patient Care, Education and Research
2005                The Leukemia and Lymphoma Society Scholar in Clinical Research Award
2005                Burroughs Wellcome Fund Clinical Scientist Award in Translational                         Research
2007                The Ohio Eminent Scholar for Stem Cell and Regenerative Medicine,                         Case Western Reserve University, School of Medicine
2007                Member, American Society of Hematology (ASH), Scientific                         Sub-committed on Stem Cell Biology
2008                Elected to the American Society of Blood and Marrow Transplantation                         (ASBMT) Board of Directors; Director of Laboratory Science
2008                Elected to the American Society of Clinical Investigation (ASCI)

Peer-Reviewed Publications

Research Support