CCCC Core Facilities

Case Comprehensive Cancer Center's Shared Resources:

• Athymic Animal Core- houses SCID and NOD-SCID mice for transplantation experiments

• Behavioral Measurement Core Facility- provides expertise in the development of new measures, and in the evaluation and interpretation of new, modified or established behavioral variables

• Biostatistics Core Facility- provides investigators with capabilities in biostatistics, clinical trials, epidemiology, statistical computing, and database and information management

• Cancer Pharmacology Core Facility - provides and sustains the laboratory, consultative, and data handling infrastructure necessary for accurate, sensitive, and valid measurement of drug and drug metabolite concentrations

• Clinical Trial Core Facility- provides investigators with a broad range of services to assist in the initiation and conduct of clinical trials

• Confocal Microscopy Core Facility- provides Conventional and Multiphoton confocal microscopy, image analysis and training

• Flow Cytometry Core Facility- provides access to cytometry and cell sorting

• Gene Expression Array Core Facility- all of the needed equipment for Affymetrix chip analysis of samples, including sample preparation, large database analysis and building of algorithms

• Hematopoietic Stem Cell Core Facility- provides procurement and distribution, processing, and analysis of human hematopoietic cell samples

• Hybridoma Core Facility - provides resource for generating and producing monoclonal antibodies to novel antigens that will enable investigators to discriminate among the proteins relevant to their research.

• Imaging Research Core Facility- 8,200 square feet of research space devoted to X-ray, PET, MRI, and SPECT imaging modalities and image analysis

• Practice-Based Research Network Core Facilty - provide infrastructure that supports the implementation of Case CCC investigators' research studies in practice-based research networks, and that supports network practice-initiated research

• Proteomics Core Facility- provides advanced mass spectrometric protein analysis methods

• Radiation Resources Core- has Cesium and Cobalt sources for irradiation of animals

• Tissue Procurement Core Facility- works to collect, prepare, and distribute high quality discarded human tissue samples to researchers studying cancer and other diseases

• Transgenic and Targeting Core Facility - provides transgenic and gene-targeted mice, in addition to pathogen control, cryopreservation and other services such as chimera, transfection, ES Cell line, training, etc.

• Translational Research Core Facility- supports Phase I/II Cancer Center research trials by providing infrastructure for laboratory correlate studies

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